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Enchantment
Whenever an opponent loses life, you gain that much life.
Even as humans regained the upper hand, some still willingly traded their lives for a chance at immortality.
Damage dealt to an opponent usually causes that opponent to lose life. An opponent paying life also causes loss of life.
wotc · 2012-05-01
If you and an opponent both lose life simultaneously, and this causes your life total to become 0 or less, you'll lose the game before Exquisite Blood's triggered ability can resolve.
wotc · 2012-05-01